Facility

Equipment Protocol

Core Facility

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Imaging devices of the Biological Signal

  • Study of the expression level of the protein
  • Study of the position of the tissue or cell
  • Physiological signal of cells: Measurement of calcium, sodium, and ROS
  • Physiological signal of mitochondria: Membrane voltage, ROS, calcium signal detection
LSM 700 from Carl Zeiss
VivaTome

Our Research

  • Changes in the calcium signal of Cardiomyocytes
  • Changes in the calcium signal of Cancer cells
  • Changes in the membrane voltage, calcium and ROS of Mitochondria

Patch Clamp

  • Understanding of the function of ion channels

Our Research

  • Changes in the Ion channel(Ca2+, K+, Na+ channel) of cardiomyocytes
  • Ion movement in the cardiomyocyte
  • Function and concentration of the ion

Organ Bath

  • Evaluation of contraction / relaxation ability of the blood vessel
  • Evaluation of contraction / relaxation ability of the blood vessels by drug

Our Research

  • Evaluation of the contraction and relaxation ability in accordance with the anatomical position of the blood vessel

Langendorff System for Mouse and rat mode; constant volume

  • Measurement of implemented pressure of the left ventricle of the heart
  • Measurement of the pressure in the right ventricle of the heart
  • Evaluation of left ventricular function of the heart

Our Research

  • Evaluation of the Cardiac toxicity of Drug
  • Evaluation of the cardioprotective effect about ischemia/reperfusion
  • Identification of a signal transduction pathway associated with a contractile force of the heart
  • Separation of cardiomyocyte

Echocardiography & Electrocardiogram (ECG)

Our Research

  • Construction of a therapeutic agent through the functional evaluation of the heart and vessels