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POWER DRUGS

  • 작성자한진
  • 작성일2005-01-30 18:16:03
  • 조회수1746
  • 첨부파일첨부파일
Technology Review; 10/1/2004; Anonymous Technology Review 10-01-2004 POWER DRUGS Byline: Anonymous Volume: 107 Number: 8 ISSN: 1099274X Publication Date: 10-01-2004 Page: 16 Section: PROTOTYPE: Straight from the lab: technology's first draft Type: Periodical Language: English PROBLEMS WITH MITOCHONDRIA-CELLS' TINY energy-producing units-can cause illnesses as diverse as cancer and Parkinson's disease. Volkmar Weissig, a pharmaceutical scientist at Northeastern University, says he's devised the first drug delivery systern that can shuttle a drug through a cell to target its mitochondria. Weissig coats drugs in a common antibacterial compound; the positively charged coating is attracted to the mitochondria, which are the most negatively charged parts of the cell. In a recent experiment with mice, Weissig found that tumors treated with the coated version of the cancer drug Taxol grew only half as much as those treated with the uncoated drug. Weissig says he could also use the approach to shuttle DNA to the mitochondria, a possible basis for gene therapy to correct mutations in mitochondrial DNA-which have been implicated in neurological diseases such as Parkinson's and Alzheimer's. A Boston startup company, MitoVec, plans to couple Weissig's technology with several existing cancer drugs and begin testing it in humans in two to three years. IMAGE PHOTOGRAPH Mitochondria are key targets for drugs. Copyright Technology Review, Inc. Oct 2004
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361 제 6회 논문연구계획서 발표대회: 최성우 학생 우수상 수상 첨부파일 2010.04.28 최성우 2010.04.28 2,859
360 다이어트 운동과 AMPK와의 관계 2010.04.20 고태희 2010.04.20 4,609
359 인슐린 생산 베타세포 재생 가능 2010.04.06 김형규 2010.04.06 3,453
358 축하합니다. 김나리 선생님: 2010 국제협력연구사업 선정 2010.03.05 한진 2010.03.05 3,581
357 동맥경화 촉진 유전자 찾아냈다...이화여대 오구택 교수 2010.02.25 허혜진 2010.02.25 3,293
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355 Prog Biophys Mol Biol논문 accept소식 2010.02.20 박원선 2010.02.20 2,662
354 Pflugers Arch논문 accept소식 2010.02.17 박원선 2010.02.17 1,912
353 장미 박사님 질병관리본부 합격 2010.02.16 박원선 2010.02.16 2,976
352 Seaons's Greetings to ALL 첨부파일 2010.01.04 한진 2010.01.04 1,663
351 안준석 제 5회 부산미래과학자상 수상자 선정 첨부파일 2009.12.02 한진 2009.12.02 4,677
350 인슐린 신호전달과 미토콘드리아 기능을 통합시키는 Foxo1 첨부파일 2009.11.24 홍다혜 2009.11.24 5,358
349 심혈관·대사질환 10대 주목 프로젝트 선정 2009.11.16 한진 2009.11.16 2,357
348 JPS논문 accept소식 2009.11.06 박원선 2009.11.06 1,724
347 Bone논문 accept소식 2009.11.05 박원선 2009.11.05 2,369
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