4th ASMRM (Asian Society for Mitochondrial Research and Medicine) Mitochondria, Metabolism and Life 2007 Date: February 2~3, 2007 Auditorium, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea http://www.k-mit.org/ http://www.k-mit.org/?doc=htm/4th/asmrm4.html 제4차 아시아미토콘드리아연구의학회 일시: 2007년 2월 2-3일 장소: 서울대학교병원 임상의학연구소 대강당 미토콘드리아는 세포내에 위치하는 소기관으로서 생과 사를 모두 담당하고 있으며 최근에 당뇨병, 비만, 암, 파킨슨병 등의 각종 퇴행성 질환 등이 미토콘드리아 기능 이상에 기인한다는 많은 증거들이 밝혀지고 있고 이들 질병에 대한 예방 및 치료의 타겟이 되고 있습니다. 2003년 2월 국내 학자들이 중심이 되어 일본, 대만, 중국과 함께 아시아 미토콘드리아연구의학회(Asian Society for Mitochondrial Research and Medicine, ASMRM)을 창립하여 매년 학술대회를 이어오고 있으며 이제 제4회 대회를 맞게 되었습니다. 이번 학회에는 미토콘드리아 연구에 있어서 최고의 석학인 미국의 Douglas Wallace 박사가 강의할 예정이며, 미토콘드리아 DNA 복제 기전의 대가인 핀란스의 Howard Jacobs 박사의 강의를 비롯하여 국내외 수많은 미토콘드리아 관련 연구자들의 강의와 연구 결과 발표가 있을 것입니다. 부디 국내의 많은 연구자들의 참여를 부탁드리는 바입니다. 제4회 아시아미토콘드리아연구의학회 준비위원회 위원장 서울대학교 의과대학 내과학교실 교수 이홍규 드림 Local Organizing Committee Chairman: Hong Kyu Lee, MD, PhD Professor Department of Internal Medicine, Seoul National University College of Medicine 28 Yongon-Dong Chongno-Gu, Seoul 110-744, Korea Phone: +82-2-2072-2266 E-mail: hkleemd@snu.ac.kr Symposium Secretary: Young Min Cho, MD, PhD Assistant Professor Department of Internal Medicine, Seoul National University College of Medicine 28 Yongon-Dong Chongno-Gu, Seoul 110-744, Korea Phone: +82-2-2072-1965 Mobile: +82-16-223-5208 E-mail: ymchomd@snu.ac.kr Members Hong Kyu Lee (Seoul National University), Ki-Up Lee (Ulsan University), Myung-shik Lee (Sungkyunkwan University), Kyong Soo Park (Seoul National University), Youngmi Kim Pak (Ulsan University), Gyesoon Yoon (Ajou University), Jin Han (Inje University), Wan Lee (Dongguk University), Eun Bo Shim (Kangwon National University), Jaewon Lee (Busan National University), Jong-Hee Chae (Seoul National University), Chae Hun Leem (Ulsan University), Jae Boum Youm (Inje University), Young Min Cho (Seoul National University) International Advisor: Yau-Huei Wei (National Yang-Ming University, Taiwan), Masashi Tanaka (Tokyo Metropolitan Institute of Gerontology, Japan), Jian-Xing Xu (Chinese Academy of Sciences, China), Zhen Yan (Duke-NUS Graduate Medical School, Singapore), Hideyuki J. Majima (Kagoshima University, Japan), Anthony W. Linnane (Center for Molecular Biology and Medicine, Australia), Keshav K. Singh (Roswell Park Cancer Institute, USA), Min-Xin Guan (Cincinnati Childeren’s Hospital Medical Center, USA), Yidong Bai (University of Texas at San Antonio, USA), Yu-ichi Goto(National Center of Neurology and Psychiatry, Japan), Shigeo Ohta (Nippon Medical School, Japan), Dongchon Kang (Kyushu University), Yusaku Nakabeppu (Kyushu University), Shusen Liu (Chinese Academy of Science, China) Important Deadlines:  Abstract submission: December 29, 2006  Pre-registration: December 29, 2006 Preliminary Program Thursday (1st February, 2007) 18:30 Reception & Welcome Party – Hotel Sofitel Ambassardor Friday (2nd February, 2007) 7:30 Registration 8:20 Opening Ceremony Hong Kyu Lee (Seoul National University, Korea) 8:30 Session 1: Evolution, Migration, and Adaptation  Identification of Mitochondrial DNA Polymorphisms That Alter Mitochondrial Matrix pH and Intracellular Calcium Dynamics (An-A Kazuno, Riken Brain Science Institute, Japan)  Mitochondrial DNA Haplogroup and Metabolic Syndrome (Young Min Cho, Seoul National University, Korea)  To Be Announced (Noboru Adachi, Yamanashi University School of Medicine, Japan)  Finding Patterns in SNP Data: Methods and Results from the Analysis of Complete mtDNA Sequences from Japan from Complex Disease and Longevity Phenotypes (Gyan Bhanot, Rutgers University, USA) 9:30 Session 2: Cell Death And Mitochondria  The Concept of Radical Metabolism of Mitochondria and Its Application in Medicine. (Jian-Xing Xu, Institute of Biophysics, Chinese Academy of Science, Beijing, China)  Importance of mtDNA Nucleoid in Maintenance of mtDNA and Prevention of Apoptosis (Dongchon Kang, Kyushu University)  A Novel Protein, Reactive Oxygen Species Modulator 1 (Romo1), Induces the Oxidative DNA Damage: Implication of Romo1 in Cancer Progression (Young Do Yoo, Korea University College of Medicine, Seoul, Korea)  Diverse mechanisms of the resistance of 0 cells against cell death (Myung-Shik Lee, Samsung Medical Center, Sungkyunkwan University) 10:30 Coffee Break 11:00 Technical Session I  High-Resolution Respirometry in Mitochondrial Physiology and Pathology (Erich Gnaiger, Innsbruck Medical University, Austria)  Diagnostic Approach for the Mitochondrial Genome Mutations and Polymorphisms – Luminex Fluorescent Bead-Based Method (Masashi Tanaka, Tokyo Metropolitan Institute of Gerontology, Japan) 12:00 Lunch 13:00 Poster Session I 14:00 Plenary Lecture 1  MtDNA, Aging and DNA Polymerase Gamma (Howard T. Jacobs, University of Tampere, Finland) 14:40 Session 3: Mitochondria-Related Diseases (I)  Clinical Diagnosis and Genetic Counseling for Mitochondrial Disorders in Japan (Yu-ichi Goto, National Institute of Neuroscience, Tokyo, Japan)  Mitochondria and Alzheimer’s Disease (Isaac Onyango, University of Virginia Health Science Center, USA)  To Be Announced (Hae Il Cheong, Seoul National University, Seoul, Korea) 15:40 Coffee Break 16:10 Special Lecture 1  CoQ10 Treatment for Mitochondrial Disorders (Anthony W. Linnane, Center for Molecular Biology and Medicine, Australia)  Essential Role of Mitochondrial Function in Adiponectin Synthesis in Adipocytes (Ki-Up Lee, University of Ulsan College of Medicine, Korea) 17:10 Session 4: Mitochondria-Related Diseases (II)  MtDNA Haplogroup and Diabetes Mellitus (Kyong Soo Park, Seoul National University, Korea)  Reduced Mitochondrial Density and Increased IRS-1 Serine Phosphorylation in Muscle of Insulin-Resistant Offspring of Type 2 Diabetic Parents (Katsutaro Morino, Shiga University Of Medical Science, Japan)  Mitochondria and Muscle Fiber Type (Chen-Yu Zhang, Nanjing University, China) 18:10 Dinner – Garden View Restaurant, Clinical Research Institute, Seoul National University Hospital Saturday (3rd February, 2007) 7:30 Registration 8:30 Session 5: Free Oral Session 9:30 Special Lecture 2  Mitochondria and Non-Apoptotic Cell Death. (Shigeomi Shimizu, Tokyo Medical & Dental University, Japan)  Mitochondrial Defect and Infertility (Chii-Ruey Tzeng, Taipei Medical University, Taiwan) 10:30 Coffee Break 11:00 Technical Session II  Analysis of Mitochondrial DNA Mutations Associated with Mitochondrial Diseases – (Yau-Huei Wei, National Yang-Ming University, Taiwan)  Multiparamer Measurement of Mitochondrial Function Using Fluorescent Probes: Simultaneous Measurement of NADH, Ca2+ and Potential (or pH) (Chae Hun Leem , University of Ulsan College of Medicine, Korea) 12:00 Lunch 13:00 Poster Session II 14:00 Plenary Lecture 2  Mitochondrial Medicine: The Energy Biology of Health and Disease (Douglas C. Wallace, University of California Irvine, USA) 14:40 Session 6: Mitochondrial Biogenesis and Proteomics  A Comparative Mitochondrial Proteomics of Human 143b TK- Osteosarcoma Cells upon Mitochondrial DNA Depletion Using ICAT and LC/MS/MS (Youngmi Kim Pak, University of Ulsan College of Medicine, Korea)  Proteomic Analysis of GSK-3 associated Proteins in Mitochondria: Insights into the Mechanism of Intramitochondrial Signal Transduction (Horng-Mo Lee, Taipei Medical University, Taipei, Taiwan)  Genetic Approaches to Identifying Mitochondrial Proteins and Their Localization (Takeaki Ozawa, National Institutes of Natural Sciences, Japan)  Dice-1 Controls the Topology of the Inner Mitochondrial Membrane In C. Elegans (Hyeon-Sook Koo, Yonsei University, Korea) 15:40 Coffee Break 16:10 Session 7: Mitochondrial Physiology and Physiome 1  Novel Functions of Mitochondrial Proton Motive Force (Shusen Liu, Institute of Zoology, Chinese Academy of Science, China)  Mitochondrial Ion Channels during Metabolic Inhibition (Han Jin, College of Medicine Inje University, Korea)  The Characteristics of Ca2+ Dynamics of Mitochondria in Ventricular Myocytes (Chae Hun Leem, University of Ulsan College of Medicine, Korea) 17:10 Session 8: Mitochondrial Physiology and Physiome 2  Ca2+ Dependence of Cardiac Mitochondria Function: Simulation and Experimental Studies (Satoshi Matsuoka, Kyoto University Graduate School of Medicine, Japan)  Mitochondria based energy system model coupled with circulation dynamics (Eun Bo Shim, Kangwon National University, Korea) 17: 50 Closing Ceremony 19:00 Banquet (N Seoul Tower, http://www.nseoultower.com) 초록접수 마감: 2006년 12월 29일 Call for Abstract The abstract submission deadline is December 29, 2006. The Scientific Program Committee invites the submission of original contributions for presentation at the 4th ASMRM. Scientific papers will normally be presented in the form of poster presentation during the conference. Several papers selected by the Local Organizing Committee will be presented in the Free Oral Session. The submission of the abstracts implies your consent to publish it in the abstract book. Please prepare your abstract in MS Word Format only. You must submit your abstract by e-mail (ymchomd@snu.ac.kr). Before submitting, please read the guidelines for preparing abstracts. Authors whose abstracts have been accepted for presentation will receive confirmation letter by January 9, 2007. Titles and Authors 1. The title should be short and concise, and indicate the contents of the abstract. 2. Title should be all in capital and bold letters. 3. The author(s) name should be typed in upper and lower case letters (first name and initials first, followed by last name). Use commas to separate the authors' names. 4. The name of the presenting author should be underlined. 5. Do not include your titles or degrees. 6. Authors should be grouped by organizations, and enter a superscript number after each name to correspond their institution (Unnecessary to use a superscript if only one author). 7. The department and organization of author(s) should be followed by a superscript number, corresponding to the author. 8. The organization name should be followed by city, state and country (no street addresses) where the work was performed. Body of Abstract 1. The text of the abstract should begin on a new line. 2. The font should be Times New Roman (including symbols) in 10 point. 3. Special characters must be inserted into the document using the INSERT SYMBOL function. 4. Ensure that your abstract is grammatically correct and free of typographical errors. 5. Abstracts will not be edited after submission. 6. Use single spacing throughout the document. 7. The text of the abstract should be a single paragraph with no sections. 8. About the use of abbreviations, spell out the name in full at the first time. It should be followed by the abbreviation in parenthesis. Do not use abbreviations in the title of the abstract. 9. The Abstract is limited to maximum one page (A4 paper size). 등록 아래 양식대로 기입하셔서 이메일로 보내주시면 됩니다. (ymchomd@snu.ac.kr). 등록비 (교재비 및 점심식사 포함) 사전등록: 5 만원 현장등록: 6 만원 송금: 신한은행 367-04-958420 (예금주: 조영민) 문의: 02-2072-1965 사전등록 마감일: 2006년 12월 29일 성명: 소속기관: 이메일: 전화번호: 입금일: 입금자: 숙박지원 안내 ASMRM 참가자가 숙박을 원하실 경우 소피텔 앰버서더 호텔을 할인 가격으로 이용하실 수 있습니다. 문의: 김경희 지배인 (Tel. 82 2 2270 3698/ Fax. 82 2 2269 7377/ M.P 82 10 6389 0184/ sofitelbg@ambatel.com) 학회장소 서울대학교 병원 임상의학연구소 대강당 (로비 아래층) 자세한 내용은 http://cri.snuh.org/intro/map.asp를 참조해 주십시오.