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MitoScan Express

  • 작성자주현
  • 작성일2005-01-30 19:04:15
  • 조회수3696
  • 첨부파일첨부파일
MitoScan Express

MitoScan Express

Rapidly Determine Impact to Mitochondrial Function
with MitoScan's in-vitro Toxicity Bioassay
The MitoScan bioassay is based on isolated vesicles of the inner membrane of mitochondria, submitochondrial particles (SMP). The prepared, frozen SMP are stable and capable of conducting electron transport and oxidative phosphorylation in-vitro.

1)  Predict whole-organism or cellular toxicity:

Use in conjunction with or in lieu of conventional bioassays requiring culturing and maintenance of organisms or cells.
2)  Screen for general cellular toxicants: SMP are sensitive to compounds that disrupt:
- Protein-membrane interactions
- Protein-protein interactions
- Protein & membrane integrity
3)  Screen for potential mitochondrial toxins: Use MitoScan in mechanistic studies to identify potential electron transport and oxidative phosphorylation inhibitors.

 Clicking on text in the image below takes you to more information on that topic. You can also use the links at bottom of the page for more details. Thanks for using MitoScan Express.

Home > MitoScan Express
For more information, click on the topic of interest to you.   Rapid
  Mitochondria- Based
  Bioassays

   Low cost

   Results in minutes

   Simple spectrophotometric
   endpoint

   Reliable predictor of whole  
   organism toxicity

   Formats available include  cuvette,  
   microplate  reader and HTS 

   No culturing of cells

   Low sample volume 

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All MitoScan Corporation products have been transferred to Harvard BioScience, Inc. Please click here to link to Harvard's World-wide-Web site. 

Copyright 2000 Harvard Bioscience, Inc.
MitoScan is a registered trademark of Harvard Bioscience, Inc.

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Photo by Karry Ritter, Madison, WI, USA

 

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